Testosterone Propionate USP 29, Ph.Eur.5.5 Micronized grade
Formula: C22H32O3 (CAS-57-85-2, ATC-G03BA03)
Molecular Weight: 344.5 gm/mol
Active life: 2-3 days
Detection time: 2-3 weeks
Anabolic/Androgenic ratio: 100:100
Testosterone Propionate is a steroid compound that is described chemically as Delta 4-androstene-17β-ol-3-one. It is the principal hormone of the testis. The ester, Propionate, is a stable, white or slightly yellow crystalline substance that is insoluble in water but freely soluble in alcohol, ether, acetone, vegetable oils, and other organic solvents. Esterification of the 17 beta-hydroxy group produces compounds which have a longer duration of action and are hydrolyzed in vivo to free testosterone.
Testosterone Propionate is a single ester testosterone compound and represents one of the most important testosterone compounds every manufactured. When synthetic testosterone was first created it was in its pure form. Simply put there was no ester attached, thereby providing a fast acting compound that would necessarily require a very frequent administration schedule. In 1937 the pharmaceutical giant Schering out of Germany would release the first ester base testosterone in Testosterone Propionate under the trade name Testoviron. The same trade name it would eventually give to its Testosterone Enanthate product. By attaching the Propionate ester to the hormone, this would allow for the hormone’s release time to be controlled and provided a more efficient means in maintaining stable blood levels. Although this was not the first synthetic testosterone preparation created, Testosterone Propionate would become the first commercially available testosterone product. It would also dominate the medical community until the 1960’s and much of the newly born performance enhancing community.
Test 600x – Buy 2 Get 1 FreeDuring the 1960’s Testosterone Propionate would lose a lot of its popularity in favor of the larger ester base Testosterone Cypionate and Testosterone Enanthate compounds. However, it is still used medicinally today as well as by many performance athletes. You will find more of it among the latter group than anywhere else. Many performance enhancing athletes actually believe the Propionate form will lead to less water retention than the dominating large ester forms of Testosterone. For this reason, it is often the preferred form of testosterone during cutting cycles. While this is the common belief it is also a misconception. Regardless of the testosterone form the hormone does not become active in the body until the ester detaches and then the hormone is released. Regardless of the ester originally attached to the hormone you still have the same testosterone hormone in the body once the ester is removed. So where does this myth come from? Common sense tells us that when running a cutting cycle the individual will consume a calorie restricted diet, one that is often healthier and with less of an abundance in carbohydrates. As a result the individual will hold less water. Then we have the fact that many often use less testosterone when dieting and if your total dose is less than an off-season dose there’s less active hormone available to promote water retention. All in all, you can receive the same benefits with Testosterone Propionate as all testosterone forms. However, an advantage of Testosterone Propionate is that it can be easier to maintain stable and peaked blood levels of the hormone due to the very frequent injection protocol compared to large ester bases.
Outside of performance enhancement, Testosterone Propionate has found a number of therapeutic uses. However, like all testosterone forms the treatment of male androgen deficiency such as low testosterone has always been the most common point of use. Testosterone Propionate has, however, also found other points of interesting use over the years in treating menopausal issues, chronic cystic mastitis, excessive lactation and endometriosis. This was for a decent amount of time the most commonly used testosterone for female medical treatment, but it has largely been removed from U.S. FDA approval in female patients. It is still approved for male use in the U.S. but it will be found in medicinal circles more commonly in other parts of the world. However, Cypionate and Enanthate remain the dominate forms worldwide leaving Propionate to be primarily use in performance circles.
Testosterone Propionate Functions & Traits:
Testosterone Propionate is a pure testosterone hormone. Although synthetic it is a perfect replica of the primary naturally produced male androgen testosterone. By design, the hormone is attached to the Propionate (propionic acid) ester, a small/short ester that enables the hormone’s release time to be controlled. Without an ester, the hormone would disperse and dissipate rapidly post administration. By attaching the ester, this promotes a controlled release and allows the individual to inject the hormone less frequently. Once Testosterone Propionate is injected, the ester slowly begins to detach from the hormone. As the ester is detached the testosterone hormone begins to release into the blood. The half-life of Testosterone Propionate is approximately two days, which is substantially longer than ester free testosterone, which carries a half-life a little less than 24 hours.
As a pure testosterone, Testosterone Propionate carries an anabolic rating of 100 and an androgenic rating of 100 as well. The testosterone hormone itself represents the basis by which all anabolic and androgenic ratings are measured in all anabolic steroids. More importantly, while carrying these structural ratings, its translating rating matches up perfectly. Testosterone Propionate will yield a notable amount of anabolic and androgenic activity. This is important as not all steroids match their structural ratings in a translating capacity.
Although synthetic in nature, Testosterone Propionate is an efficient hormone for the treatment of low testosterone. Testosterone is an essential hormone produced by men and women that affects our physical, mental and sexual wellbeing. While produced and essential for both sexes, men require approximately ten times that of women. If you suffer from low testosterone and more than 20 million men in the U.S. suffer from some type of androgen deficiency, Testosterone Propionate will remedy the problem. However, while effective, after all, it is testosterone, it is not a preferred form of treatment as it will require frequent injections. Testosterone Cypionate and Testosterone Enanthate remain the dominant forms in treatment plans. However, if you suffer and Testosterone Propionate is what’s available it is a suitable option.